PDGF+ Pre & Post Care Instructions

Pre-Treatment Instructions for PDGF+ Injections or Microneedling

To ensure the best results and minimize side effects, please follow these guidelines before your procedure:

Avoid anti-inflammatory medications such as ibuprofen (Advil, Motrin), aspirin, and naproxen (Aleve).
- Ideally, continue to avoid these for 3–4 weeks after the procedure as well.
Do not take certain supplements including Turmeric/Curcumin, Arnica, and Ginkgo Biloba before or after treatment, as these may increase bruising or bleeding.

Arrive with clean skin free of makeup, lotions, sunscreen, or any skincare products.
Wear comfortable clothing if treating the body.

Bruising, swelling, redness, and numbness are normal and may last up to several weeks after injection.
Pain hypersensitivity may occur due to PDGF’s influence on nerve excitability, sometimes felt as numbness. This is temporary and will resolve.

Time After Injection	What’s Happening
0–10 days	Bruising, mild swelling, redness, and sometimes numbness due to local nerve signaling changes.
1–3 weeks	Fibroblast activation begins with signaling and initial tissue repair and remodeling of the scaffold surrounding cells.
4–8 weeks	Collagen thickening occurs, leading to improved skin texture, plumpness and tone.
8–12 weeks	Peak visible results are seen as collagen remodeling continues.
9–12 months	Gradual decline of results; maintenance treatments may be needed.

*Individual results may vary*

Keep head elevated: Sleep slightly propped up the first night to help minimize swelling.
Stay hydrated: Drink plenty of water to support healing and skin regeneration.
Use gentle skincare: Stick with mild cleansers and moisturizers for 24–48 hours after treatment.

No touching or massaging: Avoid touching, pressing, or rubbing the injection sites for at least 24 hours.
Avoid ice packs: Swelling is expected and icing aggressively can disrupt the inflammation process that is beneficial to your results. If swelling is severe, you may ice 5 min at a time the day after.
Avoid makeup: Skip makeup for the first 12–24 hours to lower infection risk.
No alcohol, caffeine, or salty foods: These can worsen swelling and bruising.
No strenuous activity: Avoid heavy exercise, hot yoga, saunas, or steam rooms for 24–48 hours.
Avoid direct sunlight/tanning beds: Treated areas may be more sensitive—always use SPF if outdoors.

Return in 6-8 weeks for evaluation and retreatment if needed.
Mild swelling or bruising should resolve within a few weeks.
Results typically improve over several weeks as collagen production increases (usually noticeable by 8 weeks).